1fkn

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==About this Structure==
==About this Structure==
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1FKN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Additional information on 1FKN is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb79_1.html Amyloid-beta Precursor Protein] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FKN OCA].
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1FKN is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The July 2006 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Amyloid-beta Precursor Protein'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2006_7 10.2210/rcsb_pdb/mom_2006_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FKN OCA].
==Reference==
==Reference==
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Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor., Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J, Science. 2000 Oct 6;290(5489):150-3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11021803 11021803]
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<ref group="xtra">PMID:11021803</ref><references group="xtra"/>
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Ghosh, A.]]
[[Category: Ghosh, A.]]
[[Category: Hong, L.]]
[[Category: Hong, L.]]
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[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 11:02:53 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:59:11 2009''

Revision as of 03:59, 18 February 2009

Image:1fkn.png


PDB ID 1fkn

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1fkn, resolution 1.90Å ()
Non-Standard Residues:
Activity: Memapsin 2, with EC number 3.4.23.46
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR

Template:ABSTRACT PUBMED 11021803

About this Structure

1FKN is a 4 chains structure of sequences from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

Reference

  • Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803

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