2erj

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==Disease==
==Disease==
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Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes mellitus, insulin-dependent, susceptibility to, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]]
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Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]]
==About this Structure==
==About this Structure==
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2ERJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].
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2ERJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA].
==Reference==
==Reference==
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Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor., Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA, Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16477002 16477002]
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<ref group="xtra">PMID:16477002</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Debler, E W.]]
[[Category: Debler, E W.]]
[[Category: Stauber, D J.]]
[[Category: Stauber, D J.]]
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[[Category: Interleukin-2 gamma receptor]]
[[Category: Interleukin-2 gamma receptor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:44:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:00:57 2009''

Revision as of 04:01, 18 February 2009

Template:STRUCTURE 2erj

Contents

Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2

Template:ABSTRACT PUBMED 16477002

Disease

Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[147730], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

2ERJ is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002

Page seeded by OCA on Wed Feb 18 06:00:57 2009

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