This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2erj
From Proteopedia
| Line 20: | Line 20: | ||
==Disease== | ==Disease== | ||
| - | Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes mellitus, insulin-dependent, susceptibility to, 10 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]] | + | Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147730 147730]], Combined immunodeficiency, X-linked, moderate OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency, X-linked OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=308380 308380]], Severe combined immunodeficiency due to IL2 deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147680 147680]] |
==About this Structure== | ==About this Structure== | ||
| - | 2ERJ is a | + | 2ERJ is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERJ OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:16477002</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Debler, E W.]] | [[Category: Debler, E W.]] | ||
[[Category: Stauber, D J.]] | [[Category: Stauber, D J.]] | ||
| Line 37: | Line 36: | ||
[[Category: Interleukin-2 gamma receptor]] | [[Category: Interleukin-2 gamma receptor]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:00:57 2009'' |
Revision as of 04:01, 18 February 2009
Contents |
Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2
Template:ABSTRACT PUBMED 16477002
Disease
Known disease associated with this structure: Interleukin-2 receptor, alpha chain, deficiency of OMIM:[147730], Diabetes, mellitus, insulin-dependent, susceptibility to, 10 , OMIM:[147730], Combined immunodeficiency, X-linked, moderate OMIM:[308380], Severe combined immunodeficiency, X-linked OMIM:[308380], Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]
About this Structure
2ERJ is a 8 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):2788-93. Epub 2006 Feb 13. PMID:16477002
Page seeded by OCA on Wed Feb 18 06:00:57 2009
