1wt6
From Proteopedia
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{{STRUCTURE_1wt6| PDB=1wt6 | SCENE= }} | {{STRUCTURE_1wt6| PDB=1wt6 | SCENE= }} | ||
| - | + | ===Coiled-Coil domain of DMPK=== | |
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| - | ==Overview== | ||
| - | The coiled-coil domain of dystrophia myotonica protein kinase (DMPK) has been cloned, overexpressed, purified and crystallized. Two crystal forms have been obtained that belong to space groups P3 and P2(1)2(1)2(1) and diffract to 2.4 and 1.6 A resolution, respectively. Experimental phases were obtained by MAD from an SeMet derivative. The location of selenium sites used molecular-replacement phases obtained from search models lacking sequence similarity with the coiled-coil under study. Both crystal forms contain three polypeptide chains in the asymmetric unit. | ||
==About this Structure== | ==About this Structure== | ||
| - | 1WT6 is a | + | 1WT6 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WT6 OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:15583383</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Garcia, P.]] | [[Category: Garcia, P.]] | ||
[[Category: Marino, M.]] | [[Category: Marino, M.]] | ||
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[[Category: Kinase activation]] | [[Category: Kinase activation]] | ||
[[Category: Molecular replacement]] | [[Category: Molecular replacement]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:13:43 2009'' | ||
Revision as of 04:13, 18 February 2009
Coiled-Coil domain of DMPK
About this Structure
1WT6 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Garcia P, Marino M, Mayans O. Crystallization and preliminary X-ray analysis of the coiled-coil domain of dystrophia myotonica kinase. Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 2):2336-9. Epub, 2004 Nov 26. PMID:15583383 doi:10.1107/S0907444904026873
Page seeded by OCA on Wed Feb 18 06:13:43 2009
