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2nxt

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==About this Structure==
==About this Structure==
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2NXT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXT OCA].
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2NXT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NXT OCA].
==Reference==
==Reference==
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Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II., Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN, Biochemistry. 2007 Mar 27;46(12):3803-13. Epub 2007 Mar 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17330962 17330962]
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<ref group="xtra">PMID:17330962</ref><references group="xtra"/>
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Fisher, S Z.]]
[[Category: Fisher, S Z.]]
[[Category: McKenna, R.]]
[[Category: McKenna, R.]]
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[[Category: Proton transfer]]
[[Category: Proton transfer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:19:13 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:36:17 2009''

Revision as of 04:36, 18 February 2009

Image:2nxt.png

Template:STRUCTURE 2nxt

Contents

Structural and kinetic effects of hydrophobic mutations in the active site of human carbonic anhydrase II

Template:ABSTRACT PUBMED 17330962

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2NXT is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Fisher SZ, Tu C, Bhatt D, Govindasamy L, Agbandje-McKenna M, McKenna R, Silverman DN. Speeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase II. Biochemistry. 2007 Mar 27;46(12):3803-13. Epub 2007 Mar 2. PMID:17330962 doi:10.1021/bi602620k

Page seeded by OCA on Wed Feb 18 06:36:17 2009

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