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2fir
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | 2FIR is a | + | 2FIR is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA]. |
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:16757484</ref><references group="xtra"/> | |
[[Category: Coagulation factor VIIa]] | [[Category: Coagulation factor VIIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Bajaj, M S.]] | [[Category: Bajaj, M S.]] | ||
[[Category: Bajaj, S P.]] | [[Category: Bajaj, S P.]] | ||
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[[Category: Zinc]] | [[Category: Zinc]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:43:37 2009'' |
Revision as of 04:43, 18 February 2009
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| 2fir, resolution 2.00Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , , , , , , | ||||||||
| Non-Standard Residues: | |||||||||
| Gene: | F7 (Homo sapiens), F3 (Homo sapiens) | ||||||||
| Activity: | Coagulation factor VIIa, with EC number 3.4.21.21 | ||||||||
| Related: | 1dan, 2a2q, 2aer, 2b8o | ||||||||
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| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Crystal structure of DFPR-VIIa/sTF
Template:ABSTRACT PUBMED 16757484
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]
About this Structure
2FIR is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200
Page seeded by OCA on Wed Feb 18 06:43:37 2009
