2h67

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==About this Structure==
==About this Structure==
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2H67 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H67 OCA].
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2H67 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H67 OCA].
==Reference==
==Reference==
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A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog., Hua QX, Liu M, Hu SQ, Jia W, Arvan P, Weiss MA, J Biol Chem. 2006 Aug 25;281(34):24889-99. Epub 2006 May 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16728398 16728398]
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<ref group="xtra">PMID:16728398</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Arvan, P.]]
[[Category: Arvan, P.]]
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
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[[Category: Mutant]]
[[Category: Mutant]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:38:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:52:38 2009''

Revision as of 04:52, 18 February 2009

Image:2h67.png

Template:STRUCTURE 2h67

Contents

NMR structure of human insulin mutant HIS-B5-ALA, HIS-B10-ASP PRO-B28-LYS, LYS-B29-PRO, 20 structures

Template:ABSTRACT PUBMED 16728398

Disease

Known disease associated with this structure: Diabetes mellitus, rare form OMIM:[176730], Hyperproinsulinemia, familial OMIM:[176730], MODY, one form OMIM:[176730]

About this Structure

2H67 is a 2 chains structure of sequences from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Hua QX, Liu M, Hu SQ, Jia W, Arvan P, Weiss MA. A conserved histidine in insulin is required for the foldability of human proinsulin: structure and function of an ALAB5 analog. J Biol Chem. 2006 Aug 25;281(34):24889-99. Epub 2006 May 25. PMID:16728398 doi:10.1074/jbc.M602617200

Page seeded by OCA on Wed Feb 18 06:52:38 2009

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