1pw6

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==About this Structure==
==About this Structure==
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1PW6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PW6 OCA].
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1PW6 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PW6 OCA].
==Reference==
==Reference==
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Potent small-molecule binding to a dynamic hot spot on IL-2., Thanos CD, Randal M, Wells JA, J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14664558 14664558]
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<ref group="xtra">PMID:14664558</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Randal, M.]]
[[Category: Randal, M.]]
[[Category: Thanos, C D.]]
[[Category: Thanos, C D.]]
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[[Category: Il-2 interleukin 2 small molecule inhibitor]]
[[Category: Il-2 interleukin 2 small molecule inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:27:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:00:04 2009''

Revision as of 06:00, 18 February 2009

Template:STRUCTURE 1pw6

Contents

Low Micromolar Small Molecule Inhibitor of IL-2

Template:ABSTRACT PUBMED 14664558

Disease

Known disease associated with this structure: Severe combined immunodeficiency due to IL2 deficiency OMIM:[147680]

About this Structure

1PW6 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thanos CD, Randal M, Wells JA. Potent small-molecule binding to a dynamic hot spot on IL-2. J Am Chem Soc. 2003 Dec 17;125(50):15280-1. PMID:14664558 doi:10.1021/ja0382617

Page seeded by OCA on Wed Feb 18 08:00:04 2009

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