1e50

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==About this Structure==
==About this Structure==
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1E50 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E50 OCA].
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1E50 is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E50 OCA].
==Reference==
==Reference==
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Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta., Warren AJ, Bravo J, Williams RL, Rabbitts TH, EMBO J. 2000 Jun 15;19(12):3004-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10856244 10856244]
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<ref group="xtra">PMID:10856244</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
 
[[Category: Bravo, J.]]
[[Category: Bravo, J.]]
[[Category: Rabbits, T H.]]
[[Category: Rabbits, T H.]]
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[[Category: Transcription factor]]
[[Category: Transcription factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:09:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:51:11 2009''

Revision as of 06:51, 18 February 2009

Template:STRUCTURE 1e50

Contents

AML1/CBF COMPLEX

Template:ABSTRACT PUBMED 10856244

Disease

Known disease associated with this structure: Leukemia, acute myeloid OMIM:[151385], Platelet disorder, familial, with associated myeloid malignancy OMIM:[151385], Rheumatoid arthritis, susceptibility to OMIM:[151385]

About this Structure

1E50 is a 10 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Warren AJ, Bravo J, Williams RL, Rabbitts TH. Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta. EMBO J. 2000 Jun 15;19(12):3004-15. PMID:10856244 doi:10.1093/emboj/19.12.3004

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