1sl3

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==About this Structure==
==About this Structure==
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1SL3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SL3 OCA].
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1SL3 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SL3 OCA].
==Reference==
==Reference==
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Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors., Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG, J Med Chem. 2004 Jun 3;47(12):2995-3008. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15163182 15163182]
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<ref group="xtra">PMID:15163182</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
 
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Barrow, J C.]]
[[Category: Barrow, J C.]]
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[[Category: Thrombin inhibitor complex]]
[[Category: Thrombin inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 16:09:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 09:49:09 2009''

Revision as of 07:49, 18 February 2009

Image:1sl3.png

Template:STRUCTURE 1sl3

crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor

Template:ABSTRACT PUBMED 15163182

About this Structure

1SL3 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Young MB, Barrow JC, Glass KL, Lundell GF, Newton CL, Pellicore JM, Rittle KE, Selnick HG, Stauffer KJ, Vacca JP, Williams PD, Bohn D, Clayton FC, Cook JJ, Krueger JA, Kuo LC, Lewis SD, Lucas BJ, McMasters DR, Miller-Stein C, Pietrak BL, Wallace AA, White RB, Wong B, Yan Y, Nantermet PG. Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors. J Med Chem. 2004 Jun 3;47(12):2995-3008. PMID:15163182 doi:10.1021/jm030303e

Page seeded by OCA on Wed Feb 18 09:49:09 2009

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