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Nitrogenase

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Welcome to Strasbourg !
 
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J'apprend ce qu'est un [http://www-esbs.u-strasbg.fr] ! Je suis content de revoir le site de [[1ogs]].
 
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== Exploring the Structure ==
 
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<applet load='1ema' size='500' frame='true' align='right' caption='Vue en 3D de la GFP' />
 
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You can take a close look at the <scene name='Sandbox_10/1emaclaudeling/1'>chromophore</scene> of GFP in the PDB entry [[1ema]]. The backbone of the entire protein is shown here on the left. The protein chain forms a cylindrical can (shown in blue), with one portion of the strand threading straight through the middle (shown in green). The chromophore is found right in the middle of the can, totally shielded from the surrounding environment. This shielding is essential for the fluorescence. The jostling water molecules would normally rob the chromophore of its energy once it absorbs a photon. But inside the protein, it is protected, releasing the energy instead as a slightly less energetic photon of light. The chromophore (shown in the close-up on the right) forms spontaneously from three amino acids in the protein chain: a glycine, a tyrosine and a threonine (or serine). Notice how the glycine and the threonine have formed a new bond, creating an unusual five-membered ring.
 
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[[Image:Lc18 1ema.gif|550px|thumb|vignette de 1ema]]
 

Revision as of 15:33, 20 February 2009

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Eran Hodis, David Canner, Joel L. Sussman

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