Sandbox 23
From Proteopedia
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| - | <applet load='1MH1' size='300' frame='true' align='right' caption='1MH1' /> | ||
| - | This molecule contains | ||
| - | <scene name='Sandbox_23/Demo/1'>helices and sheets.</scene> | ||
| - | The crystal structure of human rac1, a member of the rho family of small G-proteins, complexed with | ||
| - | <scene name='Sandbox_23/Demo2/1'>the non-hydrolysable GTP analogue, guanosine-5'-(beta gamma-imino)triphosphate (GMPPNP)</scene> | ||
| - | , has been determined by X-ray analysis at a resolution of 1.38 A. Comparison with the structure of H-ras indicates that rac1 has an extra alpha-helical domain that is characteristic of the rho G proteins, and may be involved in the signalling pathway of this family. | ||
