3gcx
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Revision as of 13:03, 4 March 2009
Contents |
PCSK9:EGFA (pH 7.4)
Template:ABSTRACT PUBMED 19224862
Disease
Known disease associated with this structure: Hypercholesterolemia, familial OMIM:[606945]
About this Structure
3GCX is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- McNutt MC, Kwon HJ, Chen C, Chen JR, Horton JD, Lagace TA. Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells. J Biol Chem. 2009 Apr 17;284(16):10561-70. Epub 2009 Feb 17. PMID:19224862 doi:10.1074/jbc.M808802200
Page seeded by OCA on Wed Mar 4 15:03:58 2009
Categories: Homo sapiens | Chen, C. | Chen, J R. | Horton, J D. | Kwon, H J. | Lagace, T A. | McNutt, M C. | Alternative splicing | Autocatalytic cleavage | Calcium | Cholesterol metabolism | Coated pit | Disease mutation | Egf-like domain | Endocytosis | Glycoprotein | Host-virus interaction | Hydrolase | Ldl | Ldl receptor | Lipid metabolism | Lipid transport | Membrane | Pcsk9 | Phosphoprotein | Polymorphism | Protease | Protein binding | Receptor | Secreted | Serine protease | Steroid metabolism | Transmembrane | Transport | Zymogen
