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2kbi

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==Disease==
==Disease==
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Known disease associated with this structure: Brugada syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Cardiomyopathy, dilated, 1E OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Heart block, nonprogressive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Heart block, progressive, type IA OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Long QT syndrome-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Sick sinus syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Ventricular fibrillation, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]]
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Known disease associated with this structure: Brugada syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Cardiomyopathy, dilated, 1E OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Heart block, nonprogressive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Heart block, progressive, type IA OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Long QT syndrome-3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Sick sinus syndrome 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Ventricular fibrillation, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]], Sudden infant death syndrome, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600163 600163]]
==About this Structure==
==About this Structure==
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2KBI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KBI OCA].
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2KBI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KBI OCA].
==Reference==
==Reference==
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Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5., Chagot B, Potet F, Balser JR, Chazin WJ, J Biol Chem. 2008 Dec 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19074138 19074138]
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<ref group="xtra">PMID:19074138</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Balser, J R.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Chagot, B.]]
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[[Category: Chazin, W J.]]
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[[Category: Potet, F.]]
[[Category: Brugada syndrome]]
[[Category: Brugada syndrome]]
[[Category: Cardiomyopathy]]
[[Category: Cardiomyopathy]]
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[[Category: Voltage-gated channel]]
[[Category: Voltage-gated channel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 20:13:27 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 18 20:07:37 2009''

Revision as of 18:07, 18 March 2009

Image:2kbi.png

Template:STRUCTURE 2kbi

Contents

Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5

Template:ABSTRACT PUBMED 19074138

Disease

Known disease associated with this structure: Brugada syndrome 1 OMIM:[600163], Cardiomyopathy, dilated, 1E OMIM:[600163], Heart block, nonprogressive OMIM:[600163], Heart block, progressive, type IA OMIM:[600163], Long QT syndrome-3 OMIM:[600163], Sick sinus syndrome 1 OMIM:[600163], Ventricular fibrillation, idiopathic OMIM:[600163], Sudden infant death syndrome, susceptibility to OMIM:[600163]

About this Structure

2KBI is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chagot B, Potet F, Balser JR, Chazin WJ. Solution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5. J Biol Chem. 2009 Mar 6;284(10):6436-45. Epub 2008 Dec 11. PMID:19074138 doi:10.1074/jbc.M807747200

Page seeded by OCA on Wed Mar 18 20:07:37 2009

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