Sandbox11
From Proteopedia
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==References== | ==References== | ||
[http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=567]Entrez Gene: B2M | [http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=567]Entrez Gene: B2M | ||
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| + | [http://www.russell.embl.de/aas/hydrophobic.html] list of hydrophobic amino acids | ||
Revision as of 02:35, 19 March 2009
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
K Sniffen 3/3/09, Keith Barbato, Jonathan Rymasz 3/18/09
Name
beta-2-microglobulin
About this Structure
This protein consists of seven shown here in purple. It also has a small on the surface of the protein shown in teal. Notice also, the , which allows for binding to occur. Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells (Gussow et al., 1987 [PubMed 3312414])[1]
Here's a bond!!
There is a hydrophobic element to B2M. When all of the most hydrophobic residues are selected, it can be clearly seen that there is a between the two Beta sheets. Speculation could say that it has evolved in this manner to protect the .
References
[1]Entrez Gene: B2M
[2] list of hydrophobic amino acids
