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Triose Phosphate Isomerase
From Proteopedia
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=== Triose Phosphate Isomerase Deficiency === | === Triose Phosphate Isomerase Deficiency === | ||
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== See Also == | == See Also == | ||
Revision as of 00:20, 20 March 2009
'Triose Phosphate Isomerase
Contents |
Overview
(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.
Mechanism
TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition>
Acid Base Catalysis
Diagram .<ref name= "web.virginia.edu" [1]
Structure & Function
Disease
Triose Phosphate Isomerase Deficiency
'Triose_Phosphate_Isomerase/Alpha_helices_and_beta_sheets/2'
See Also
References
Triose Phosphate Isomerase [[2]] Triose Phosphate Isomerase Deficiency [[3]]
Proteopedia Page Contributors and Editors (what is this?)
Gregg Snider, Eric Martz, Michal Harel, Alexander Berchansky, David Canner, Eran Hodis, Stephen Everse, Angel Herraez, Jane S. Richardson
![[1]](http://web.virginia.edu/Heidi/chapter19/Images/8883n19_15.jpg){kind=link}