Triose Phosphate Isomerase

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== Structure & Function ==
== Structure & Function ==
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=== Triose Phosphate Isomerase Deficiency ===
=== Triose Phosphate Isomerase Deficiency ===
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== See Also ==
== See Also ==

Revision as of 00:20, 20 March 2009

'Triose Phosphate Isomerase

Image:TPI2.png

Template:STRUCTURE 1tim


Contents

Overview

(TPI or TIM) which catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate, an essential process in the glycolytic pathway.


Mechanism

TPI catalyzes the transfer of a hydrogen atom from carbon 1 to carbon 2, an intramolecular oxidation-reduction. This isomerization of a ketose to an aldose proceeds through an enediol intermediate.<Biochemistry 6th Edition>

Acid Base Catalysis

Image:TPI mechanism.jpg

Diagram .<ref name= "web.virginia.edu" [1]

Structure & Function

Disease

Triose Phosphate Isomerase Deficiency

'Triose_Phosphate_Isomerase/Alpha_helices_and_beta_sheets/2'

See Also

References

 Triose Phosphate Isomerase [[2]]
Triose Phosphate Isomerase Deficiency [[3]]
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