3e88

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==About this Structure==
==About this Structure==
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3E88 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E88 OCA].
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3E88 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E88 OCA].
==Reference==
==Reference==
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Aminofurazans as potent inhibitors of AKT kinase., Rouse MB, Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA, Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/19179070 19179070]
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<ref group="xtra">PMID:19179070</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Protein complex]]
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[[Category: Concha, N O.]]
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[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
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[[Category: Elkins, P A.]]
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[[Category: Smallwood, A.]]
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[[Category: Ward, P.]]
[[Category: Akt2]]
[[Category: Akt2]]
[[Category: Alternative splicing]]
[[Category: Alternative splicing]]
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[[Category: Wnt signaling pathway]]
[[Category: Wnt signaling pathway]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 18 20:27:04 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 22 10:30:48 2009''

Revision as of 08:30, 22 March 2009

Image:3e88.png

Template:STRUCTURE 3e88

Contents

Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

Template:ABSTRACT PUBMED 19179070

Disease

Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]

About this Structure

3E88 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Rouse MB, Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA. Aminofurazans as potent inhibitors of AKT kinase. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9. PMID:19179070 doi:10.1016/j.bmcl.2009.01.002

Page seeded by OCA on Sun Mar 22 10:30:48 2009

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