3fqf

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3fqf.jpg|left|200px]]
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The entry 3fqf is ON HOLD until Paper Publication
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{{STRUCTURE_3fqf| PDB=3fqf | SCENE= }}
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Authors: Anderson, A.C., Frey, K.M., Liu, J., Lombardo, M.N.
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===Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)===
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Description: Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 4 11:23:13 2009''
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{{ABSTRACT_PUBMED_19249312}}
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==About this Structure==
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3FQF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_rf122 Staphylococcus aureus rf122]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FQF OCA].
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==Reference==
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<ref group="xtra">PMID:19249312</ref><references group="xtra"/>
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[[Category: Dihydrofolate reductase]]
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[[Category: Staphylococcus aureus rf122]]
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[[Category: Anderson, A C.]]
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[[Category: Frey, K M.]]
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[[Category: Liu, J.]]
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[[Category: Lombardo, M N.]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:32:47 2009''

Revision as of 10:32, 25 March 2009

Image:3fqf.jpg

Template:STRUCTURE 3fqf

Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)

Template:ABSTRACT PUBMED 19249312

About this Structure

3FQF is a 1 chain structure of sequence from Staphylococcus aureus rf122. Full crystallographic information is available from OCA.

Reference

  • Frey KM, Liu J, Lombardo MN, Bolstad DB, Wright DL, Anderson AC. Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance. J Mol Biol. 2009 Apr 17;387(5):1298-308. Epub 2009 Feb 26. PMID:19249312 doi:10.1016/j.jmb.2009.02.045

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