User:Michael Skovbo Windahl/sandbox
From Proteopedia
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| - | Tryptophan hydroxylase is an iron and tetrahydrobiopterin dependent monooxygenase. | + | [[Tryptophan hydroxylase]] is an iron and tetrahydrobiopterin dependent monooxygenase which belongs to the enzyme family of [[aromatic amino acid hydroxylases]]. |
{{STRUCTURE_3e2t| PDB=3e2t | SCENE= }} | {{STRUCTURE_3e2t| PDB=3e2t | SCENE= }} | ||
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The <scene name='User:Michael_Skovbo_Windahl/sandbox/3e2t_iron_coordination/1'>iron is coordinated</scene> by 2 histidines, one glutamate and one imidazole from the solvent. | The <scene name='User:Michael_Skovbo_Windahl/sandbox/3e2t_iron_coordination/1'>iron is coordinated</scene> by 2 histidines, one glutamate and one imidazole from the solvent. | ||
| - | This coordination is called the 2-histidine-1-glutamate facial triad iron coordination and is seen in many mononuclear non-heme iron(II)enzymes <ref>PMID: 15739104<ref/> | + | This coordination is called the 2-histidine-1-glutamate facial triad iron coordination and is seen in many mononuclear non-heme iron(II)enzymes <ref>PMID: 15739104<ref/>. In this structure glutamate coordinates in a partial bidentate manner. |
==References== | ==References== | ||
<references /> | <references /> | ||
Revision as of 13:34, 7 April 2009
This is a sandbox
Tryptophan hydroxylase is an iron and tetrahydrobiopterin dependent monooxygenase which belongs to the enzyme family of aromatic amino acid hydroxylases.
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| 3e2t, resolution 1.90Å () | |||||||||
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| Ligands: | , , , , | ||||||||
| Activity: | Tryptophan 5-monooxygenase, with EC number 1.14.16.4 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
The by 2 histidines, one glutamate and one imidazole from the solvent. This coordination is called the 2-histidine-1-glutamate facial triad iron coordination and is seen in many mononuclear non-heme iron(II)enzymes [1]
