User:Karl E. Zahn/Sandbox RB69 1/domain-structure
From Proteopedia
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(New page: DNA polymerases (pols) are a specialized class of transferase enzymes that catalyze template directed extension of a primed DNA. The family B DNA pol encoded in the genome of the bacterio...) |
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| - | DNA polymerases (pols) are a specialized class of transferase enzymes that catalyze template directed extension of a primed DNA. The family B DNA pol encoded in the genome of the bacteriophage RB69 represents such an enzyme that shares significant homology with the human primase associated pol α, the human replicative | + | DNA polymerases (pols) are a specialized class of transferase enzymes that catalyze template directed extension of a primed DNA. The family B DNA pol encoded in the genome of the bacteriophage RB69 represents such an enzyme that shares significant homology with the human primase associated pol α, the human replicative pols δ and ε, and the human repair pol ζ. The relative ease with which one can induce RB69 pol to form diffraction quality crystals in complex with DNA has allowed RB69 pol to serve as an extremely useful structural tool and model of human enzymes. |
Revision as of 20:26, 16 April 2009
DNA polymerases (pols) are a specialized class of transferase enzymes that catalyze template directed extension of a primed DNA. The family B DNA pol encoded in the genome of the bacteriophage RB69 represents such an enzyme that shares significant homology with the human primase associated pol α, the human replicative pols δ and ε, and the human repair pol ζ. The relative ease with which one can induce RB69 pol to form diffraction quality crystals in complex with DNA has allowed RB69 pol to serve as an extremely useful structural tool and model of human enzymes.
