NS5B

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<applet load='2HAI_catalytic3.pdb' size='400' frame='true' align='right' caption='PDB ID 2HAI' />Placeholder, type here.
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<applet load='2HAI_catalytic3.pdb' size='600' frame='true' align='right' caption='PDB ID 2HAI' />Placeholder, type here.
[[Image:1NB4_4domains.jpg]]
[[Image:1NB4_4domains.jpg]]
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<applet load='2HAI_DNA5.pdb' size='400' frame='true' align='right' caption='PDB IDs 2HAI (protein) 1RTD (DNA)' />NS5B with B form DNA from HIV Reverse Transcriptase co-crystal model. DNA was modeled in by alignment of palms domain. A beta hairpin in the thumb domain has been moved to accommodate DNA, the hairpin is modeled into the minor groove, a possible binding site.
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<applet load='2HAI_DNA5.pdb' size='600' frame='true' align='right' caption='PDB IDs 2HAI (protein) 1RTD (DNA)' />NS5B with B form DNA from HIV Reverse Transcriptase co-crystal model. DNA was modeled in by alignment of palms domain. A beta hairpin in the thumb domain has been moved to accommodate DNA, the hairpin is modeled into the minor groove, a possible binding site.

Revision as of 06:03, 20 April 2009

NS5B, the RNA Dependent RNA Polymerase from Hepatitis C Virus

PDB ID 2HAI

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Placeholder, type here.

Image:1NB4 4domains.jpg

PDB IDs 2HAI (protein) 1RTD (DNA)

Drag the structure with the mouse to rotate
NS5B with B form DNA from HIV Reverse Transcriptase co-crystal model. DNA was modeled in by alignment of palms domain. A beta hairpin in the thumb domain has been moved to accommodate DNA, the hairpin is modeled into the minor groove, a possible binding site.
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