User:Riki Stevenson/Sandbox 1
From Proteopedia
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| - | <applet load='1rhg' size='300' frame='true' align='right' caption='Insert caption here' /> | + | |
| - | + | == '''Granulocyte colony-stimulating factor (G-CSF or GCSF)''' == | |
| + | <applet load='1rhg' size='300' frame='true' align='right' caption='Insert caption here' /> | ||
| + | is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to release them into the blood. It also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. G-CSF is also known as colony-stimulating factor 3 (CSF 3).''' | ||
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| + | == Structure == | ||
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<scene name='User:Riki_Stevenson/Sandbox_1/Secondary_structure_from_side/1'>Secondary structures</scene> are highlighted here, with multiple alpha-helices. The two disulfides are also shown in this view. | <scene name='User:Riki_Stevenson/Sandbox_1/Secondary_structure_from_side/1'>Secondary structures</scene> are highlighted here, with multiple alpha-helices. The two disulfides are also shown in this view. | ||
<scene name='User:Riki_Stevenson/Sandbox_1/Secondary_structure_from_top/1'>The same elements</scene> seen from the top view. | <scene name='User:Riki_Stevenson/Sandbox_1/Secondary_structure_from_top/1'>The same elements</scene> seen from the top view. | ||
Revision as of 21:22, 27 April 2009
Granulocyte colony-stimulating factor (G-CSF or GCSF)
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is a colony-stimulating factor hormone. It is a glycoprotein, growth factor or cytokine produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to release them into the blood. It also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. G-CSF is also known as colony-stimulating factor 3 (CSF 3).
Structure
are highlighted here, with multiple alpha-helices. The two disulfides are also shown in this view. seen from the top view.
When structures are colored by , it accentuates regions of structural movement and least fixed.
(purple/grey) show how charged residues tend to congregate on the exterior of the structure.
