3fl8

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3fl8.jpg|left|200px]]
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The entry 3fl8 is ON HOLD
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{{STRUCTURE_3fl8| PDB=3fl8 | SCENE= }}
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Authors: Bourne, C.R., Barrow, W.W.
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===Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative===
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Description: Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 7 09:35:32 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19364848 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19364848}}
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==About this Structure==
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3FL8 is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL8 OCA].
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==Reference==
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<ref group="xtra">PMID:19364848</ref><references group="xtra"/>
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[[Category: Bacillus anthracis]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Barrow, W W.]]
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[[Category: Bourne, C R.]]
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[[Category: Dihydrophthalazine]]
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[[Category: Oxidoreductase]]
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[[Category: Pyrimidine]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 30 09:42:30 2009''

Revision as of 06:42, 30 April 2009

Image:3fl8.jpg

Template:STRUCTURE 3fl8

Crystal structure of B. anthracis dihydrofolate reductase (DHFR) with RAB1, a TMP-dihydrophthalazine derivative

Template:ABSTRACT PUBMED 19364848

About this Structure

3FL8 is a 8 chains structure of sequences from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  • Bourne CR, Bunce RA, Bourne PC, Berlin KD, Barrow EW, Barrow WW. Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity. Antimicrob Agents Chemother. 2009 Jul;53(7):3065-73. Epub 2009 Apr 13. PMID:19364848 doi:10.1128/AAC.01666-08

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