1fkn

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{{STRUCTURE_1fkn| PDB=1fkn | SCENE= }}
{{STRUCTURE_1fkn| PDB=1fkn | SCENE= }}
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===STRUCTURE OF BETA-SECRETASE COMPLEXED WITH INHIBITOR===
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===Structure of Beta-Secretase Complexed with Inhibitor===
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[[Category: Amyloid-beta Precursor Protein]]
[[Category: Amyloid-beta Precursor Protein]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
 +
[[Category: Memapsin 2]]
[[Category: Ghosh, A.]]
[[Category: Ghosh, A.]]
[[Category: Hong, L.]]
[[Category: Hong, L.]]
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[[Category: Base]]
[[Category: Base]]
[[Category: Beta-secretase]]
[[Category: Beta-secretase]]
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[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:59:11 2009''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 6 09:11:53 2009''

Revision as of 06:11, 6 May 2009


PDB ID 1fkn

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1fkn, resolution 1.90Å ()
Non-Standard Residues:
Activity: Memapsin 2, with EC number 3.4.23.46
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Structure of Beta-Secretase Complexed with Inhibitor

Template:ABSTRACT PUBMED 11021803

About this Structure

1FKN is a 4 chains structure of sequences from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. Full crystallographic information is available from OCA.

Reference

  • Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803

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