3d28
From Proteopedia
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| + | {{STRUCTURE_3d28| PDB=3d28 | SCENE= }} | ||
| - | + | ===Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor=== | |
| - | Description: Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_18554907}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 18554907 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_18554907}} | ||
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| + | ==About this Structure== | ||
| + | 3D28 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D28 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:18554907</ref><references group="xtra"/> | ||
| + | [[Category: RNA-directed RNA polymerase]] | ||
| + | [[Category: Viruses]] | ||
| + | [[Category: Han, Q.]] | ||
| + | [[Category: Kissinger, C R.]] | ||
| + | [[Category: Showalter, R E.]] | ||
| + | [[Category: Zhao, Q.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleotidyltransferase]] | ||
| + | [[Category: Protein-ligand complex]] | ||
| + | [[Category: Rna-directed rna polymerase]] | ||
| + | [[Category: Transcription]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:16:00 2009'' | ||
Revision as of 14:16, 20 May 2009
Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor
Template:ABSTRACT PUBMED 18554907
About this Structure
3D28 is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.
Reference
- Kim SH, Tran MT, Ruebsam F, Xiang AX, Ayida B, McGuire H, Ellis D, Blazel J, Tran CV, Murphy DE, Webber SE, Zhou Y, Shah AM, Tsan M, Showalter RE, Patel R, Gobbi A, LeBrun LA, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L, Zhao Q, Han Q, Kissinger CR. Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4181-5. Epub 2008 May 24. PMID:18554907 doi:10.1016/j.bmcl.2008.05.083
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