2wf0
From Proteopedia
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| + | {{STRUCTURE_2wf0| PDB=2wf0 | SCENE= }} | ||
| - | + | ===HUMAN BACE-1 IN COMPLEX WITH 4-ETHYL-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-8-(2-OXO-1-PYRROLIDINYL)-6-QUINOLINECARBOXAMIDE=== | |
| - | Description: Human BACE-1 in complex with 4-ethyl-N-((1S,2R)-2-hydroxy-1-( phenylmethyl)-3-(((3-(trifluoromethyl)phenyl)methyl)amino)propyl)-8-( 2-oxo-1-pyrrolidinyl)-6-quinolinecarboxamide | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19428244}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19428244 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19428244}} | ||
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| + | ==About this Structure== | ||
| + | 2WF0 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WF0 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19428244</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Brien, A O.]] | ||
| + | [[Category: Charrier, N.]] | ||
| + | [[Category: Clarke, B.]] | ||
| + | [[Category: Cutler, L.]] | ||
| + | [[Category: Demont, E.]] | ||
| + | [[Category: Dingwall, C.]] | ||
| + | [[Category: Dunsdon, R.]] | ||
| + | [[Category: Hawkins, J.]] | ||
| + | [[Category: Howes, C.]] | ||
| + | [[Category: Hubbard, J.]] | ||
| + | [[Category: Hussain, I.]] | ||
| + | [[Category: Maile, G.]] | ||
| + | [[Category: Matico, R.]] | ||
| + | [[Category: Mosley, J.]] | ||
| + | [[Category: Naylor, A.]] | ||
| + | [[Category: Redshaw, S.]] | ||
| + | [[Category: Rowland, P.]] | ||
| + | [[Category: Smith, K J.]] | ||
| + | [[Category: Soleil, V.]] | ||
| + | [[Category: Sweitzer, S.]] | ||
| + | [[Category: Theobald, P.]] | ||
| + | [[Category: Vesey, D.]] | ||
| + | [[Category: Walter, D S.]] | ||
| + | [[Category: Wayne, G.]] | ||
| + | [[Category: Alternative splicing]] | ||
| + | [[Category: Asp-2]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Bace-1]] | ||
| + | [[Category: Beta-secretase]] | ||
| + | [[Category: Beta-site app cleaving enzyme]] | ||
| + | [[Category: Disulfide bond]] | ||
| + | [[Category: Glycoprotein]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Memapsin-2]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Transmembrane]] | ||
| + | [[Category: Zymogen]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 17:20:01 2009'' | ||
Revision as of 14:20, 20 May 2009
HUMAN BACE-1 IN COMPLEX WITH 4-ETHYL-N-((1S,2R)-2-HYDROXY-1-(PHENYLMETHYL)-3-(((3-(TRIFLUOROMETHYL)PHENYL)METHYL)AMINO) PROPYL)-8-(2-OXO-1-PYRROLIDINYL)-6-QUINOLINECARBOXAMIDE
Template:ABSTRACT PUBMED 19428244
About this Structure
2WF0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Charrier N, Clarke B, Cutler L, Demont E, Dingwall C, Dunsdon R, Hawkins J, Howes C, Hubbard J, Hussain I, Maile G, Matico R, Mosley J, Naylor A, O'Brien A, Redshaw S, Rowland P, Soleil V, Smith KJ, Sweitzer S, Theobald P, Vesey D, Walter DS, Wayne G. Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3664-8. Epub 2009 Apr 17. PMID:19428244 doi:10.1016/j.bmcl.2009.03.165
Page seeded by OCA on Wed May 20 17:20:01 2009
Categories: Homo sapiens | Memapsin 2 | Brien, A O. | Charrier, N. | Clarke, B. | Cutler, L. | Demont, E. | Dingwall, C. | Dunsdon, R. | Hawkins, J. | Howes, C. | Hubbard, J. | Hussain, I. | Maile, G. | Matico, R. | Mosley, J. | Naylor, A. | Redshaw, S. | Rowland, P. | Smith, K J. | Soleil, V. | Sweitzer, S. | Theobald, P. | Vesey, D. | Walter, D S. | Wayne, G. | Alternative splicing | Asp-2 | Aspartyl protease | Bace-1 | Beta-secretase | Beta-site app cleaving enzyme | Disulfide bond | Glycoprotein | Hydrolase | Memapsin-2 | Membrane | Polymorphism | Protease | Transmembrane | Zymogen
