3gxt

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3gxt.jpg|left|200px]]
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The entry 3gxt is ON HOLD
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{{STRUCTURE_3gxt| PDB=3gxt | SCENE= }}
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Authors: Lieberman, R.L.
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===Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin===
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Description: Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 20 16:36:58 2009''
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{{ABSTRACT_PUBMED_19374450}}
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==Disease==
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Known disease associated with this structure: Fabry disease OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300644 300644]], Fabry disease, cardiac variant OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300644 300644]]
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==About this Structure==
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3GXT is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GXT OCA].
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==Reference==
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<ref group="xtra">PMID:19374450</ref><references group="xtra"/>
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[[Category: Alpha-galactosidase]]
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[[Category: Homo sapiens]]
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[[Category: Lieberman, R L.]]
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[[Category: Disease mutation]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Glycosidase]]
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[[Category: Hydrolase]]
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[[Category: Lysosome]]
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[[Category: Pharmaceutical]]
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[[Category: Rna editing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 27 15:22:49 2009''

Revision as of 12:22, 27 May 2009

Image:3gxt.jpg

Template:STRUCTURE 3gxt

Contents

Crystal structure of alpha-galactosidase A at pH 4.5 complexed with 1-deoxygalactonijirimycin

Template:ABSTRACT PUBMED 19374450

Disease

Known disease associated with this structure: Fabry disease OMIM:[300644], Fabry disease, cardiac variant OMIM:[300644]

About this Structure

3GXT is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability. Biochemistry. 2009 May 1. PMID:19374450 doi:http://dx.doi.org/10.1021/bi9002265

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