2k9r
From Proteopedia
(Difference between revisions)
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==About this Structure== | ==About this Structure== | ||
- | 2K9R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full | + | 2K9R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9R OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Secreted]] | [[Category: Secreted]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 16:32:05 2009'' |
Revision as of 13:32, 10 June 2009
Contents |
Enhancing the activity of insulin by stereospecific unfolding
Template:ABSTRACT PUBMED 19321436
Disease
Known disease associated with this structure: Hyperproinsulinemia, familial, with or without diabetes OMIM:[176730]
About this Structure
2K9R is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Hua QX, Xu B, Huang K, Hu SQ, Nakagawa S, Jia W, Wang S, Whittaker J, Katsoyannis PG, Weiss MA. Enhancing the activity of a protein by stereospecific unfolding: conformational life cycle of insulin and its evolutionary origins. J Biol Chem. 2009 May 22;284(21):14586-96. Epub 2009 Mar 25. PMID:19321436 doi:10.1074/jbc.M900085200
Page seeded by OCA on Wed Jun 10 16:32:05 2009
Categories: Homo sapiens | Hu, S Q. | Hua, Q X. | Huang, K. | Jia, W H. | Katsoyannis, P G. | Nakarawa, S. | Philips, N F.P. | Weiss, M A. | Wittaker, J. | Wittaker, L. | Xu, B. | Carbohydrate metabolism | Cleavage on pair of basic residue | Diabetes mellitus | Disease mutation | Glucose metabolism | Hormone | Insulin | Mutant | Pharmaceutical | Secreted