This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1rau
From Proteopedia
OCA (Talk | contribs)
(New page: 200px<br /><applet load="1rau" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rau" /> '''SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RN...)
Next diff →
Revision as of 20:19, 24 November 2007
|
SOLUTION STRUCTURE OF AN UNUSUALLY STABLE RNA TETRAPLEX CONTAINING G-AND U-QUARTET STRUCTURES
Overview
A model for the solution structure of an RNA tetraplex, (rUGGGGU)4, has, been obtained by two-dimensional NMR spectroscopy and molecular dynamics., The molecule is parallel stranded and Hoogsteen base-paired in 50 mM KCl, and it is so stable that three of its six imino protons have exchange, half-lives measured in days at 40 degrees C. The tetraplex is stabilized, by base stacking and by the hydrogen bonds in four G quartets and at least, one U quartet. This is the first indication of the existence of U-quartet, structures of which we are aware.
About this Structure
1RAU is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures., Cheong C, Moore PB, Biochemistry. 1992 Sep 15;31(36):8406-14. PMID:1382577
Page seeded by OCA on Sat Nov 24 22:27:11 2007
Categories: Protein complex | Cheong, C. | Moore, P.B. | Nmr | Rna | Tetraplex
