2kfx

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'''Unreleased structure'''
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{{Seed}}
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[[Image:2kfx.jpg|left|200px]]
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The entry 2kfx is ON HOLD until Paper Publication
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{{STRUCTURE_2kfx| PDB=2kfx | SCENE= }}
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Authors: Hoffman, R.M.B., Sykes, B.D.
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===Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7===
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Description: Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 15 09:37:11 2009''
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{{ABSTRACT_PUBMED_19419198}}
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==About this Structure==
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2KFX is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KFX OCA].
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==Reference==
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<ref group="xtra">PMID:19419198</ref><ref group="xtra">PMID:10387074</ref><ref group="xtra">PMID:12060657</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Hoffman, R M.B.]]
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[[Category: Sykes, B D.]]
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[[Category: Acetylation]]
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[[Category: Calcium]]
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[[Category: Calcium regulation]]
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[[Category: Cardiac]]
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[[Category: Cardiomyopathy]]
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[[Category: Cardiotonic drug]]
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[[Category: Disease mutation]]
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[[Category: Metal binding protein]]
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[[Category: Muscle protein]]
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[[Category: Polymorphism]]
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[[Category: Striated muscle]]
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[[Category: Troponin]]
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[[Category: W7]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 17:55:28 2009''

Revision as of 14:55, 10 June 2009

Image:2kfx.jpg

Template:STRUCTURE 2kfx

Structure of the N-terminal domain of human cardiac troponin C bound to calcium ion and to the inhibitor W7

Template:ABSTRACT PUBMED 19419198

About this Structure

2KFX is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hoffman RM, Sykes BD. Structure of the Inhibitor W7 Bound to the Regulatory Domain of Cardiac Troponin C. Biochemistry. 2009 May 21. PMID:19419198 doi:10.1021/bi9001826
  • Li MX, Spyracopoulos L, Sykes BD. Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac troponin-C. Biochemistry. 1999 Jun 29;38(26):8289-98. PMID:10387074 doi:10.1021/bi9901679
  • Wang X, Li MX, Sykes BD. Structure of the regulatory N-domain of human cardiac troponin C in complex with human cardiac troponin I147-163 and bepridil. J Biol Chem. 2002 Aug 23;277(34):31124-33. Epub 2002 Jun 11. PMID:12060657 doi:10.1074/jbc.M203896200

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