3ewj
From Proteopedia
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===Crystal structure of catalytic domain of TACE with carboxylate inhibitor=== | ===Crystal structure of catalytic domain of TACE with carboxylate inhibitor=== | ||
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==About this Structure== | ==About this Structure== | ||
3EWJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWJ OCA]. | 3EWJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWJ OCA]. | ||
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+ | ==Reference== | ||
+ | <ref group="xtra">PMID:19054672</ref><references group="xtra"/> | ||
[[Category: ADAM 17 endopeptidase]] | [[Category: ADAM 17 endopeptidase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 15:10, 10 June 2009
Crystal structure of catalytic domain of TACE with carboxylate inhibitor
Template:ABSTRACT PUBMED 19054672
About this Structure
3EWJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Guo Z, Orth P, Wong SC, Lavey BJ, Shih NY, Niu X, Lundell DJ, Madison V, Kozlowski JA. Discovery of novel spirocyclopropyl hydroxamate and carboxylate compounds as TACE inhibitors. Bioorg Med Chem Lett. 2009 Jan 1;19(1):54-7. Epub 2008 Nov 14. PMID:19054672 doi:10.1016/j.bmcl.2008.11.034
Page seeded by OCA on Wed Jun 10 18:10:12 2009
Categories: ADAM 17 endopeptidase | Homo sapiens | Orth, P. | Adam17 | Alternative splicing | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Tace | Transmembrane | Zinc | Zymogen