User:Tilman Schirmer/Sandbox 201

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(1.8 Activated conformation)
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[[Image:1w25_small.png|frame|left|non-activated (1w25)]] [[Image:2v0n_small_smaller2.png|frame|center|activated (BeF3- modified; 2v0n]]
[[Image:1w25_small.png|frame|left|non-activated (1w25)]] [[Image:2v0n_small_smaller2.png|frame|center|activated (BeF3- modified; 2v0n]]
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<applet load='1w25' scene='User:Tilman_Schirmer/Sandbox_201/Loose_dimer/2' size='300' frame='true' align='left' caption='1w25' /> <applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Tight_dimer/2' size='300' frame='true' align='center' caption='2v0n' />
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Revision as of 10:42, 19 June 2009

Diguanylate cyclases

Contents

1. PleD

1.1 Intro


1.2 Domain structure


1.3 Protomer

2v0n

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: , ,




















1.4 Substrate binding site


1.5 Allosteric product binding site


1.5.1 C-di-GMP


1.5.2 Primary inhibition site (Ip)


1.5.3 Secondary inhibition site (Is)


1.6 Two conformations

non-activated (1w25)
non-activated (1w25)
activated (BeF3- modified; 2v0n
activated (BeF3- modified; 2v0n


1w25

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2v0n

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1.7 Non-activated conformation

1w25

1w25

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: , ,



















1.8 Activated conformation

2v0n

2v0n

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2. WspR

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Tilman Schirmer

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