User:Tilman Schirmer/Sandbox 201

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(Protomer)
(Protomer)
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== Protomer ==
== Protomer ==
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<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Protomer_activeated/1' size='300' frame='true' align='right' caption='2v0n' />
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<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Protomer_activeated/1' size='300' frame='true' align='right' caption='Diguanylate cyclase PleD (1w25)' />
<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/4'>Protomer</scene>: <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_rec/1'>Rec</scene>, <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_rec2/1'>Rec'</scene>, <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_ggdef/1'>GGDEF</scene>
<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer/4'>Protomer</scene>: <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_rec/1'>Rec</scene>, <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_rec2/1'>Rec'</scene>, <scene name='User:Tilman_Schirmer/Sandbox_201/Activated_ggdef/1'>GGDEF</scene>
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<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_ggdef/1'>GGDEF</scene>
<scene name='User:Tilman_Schirmer/Sandbox_201/Protomer_ggdef/1'>GGDEF</scene>
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<br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br>
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== Substrate binding site ==
== Substrate binding site ==

Revision as of 18:55, 20 June 2009

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PleD

Contents

Intro

Domain structure

Protomer

Diguanylate cyclase PleD (1w25)

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: , ,





Substrate binding site

2v0n

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Allosteric product binding site

Allosteric product binding site

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C-di-GMP


Primary inhibition site (Ip)


Secondary inhibition site (Is)


Primary and secondary inhibition sites





Two conformations

non-activated (1w25)
non-activated (1w25)
activated (BeF3- modified; 2v0n)
activated (BeF3- modified; 2v0n)


non-activated (1w25)

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activated (BeF3- modified; 2v0n)

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Non-activated conformation

1w25

1w25

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: , ,



















Activated conformation

2v0n

2v0n

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Tilman Schirmer

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