User:Tilman Schirmer/Sandbox 201

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== Intro ==
== Intro ==

Revision as of 19:48, 20 June 2009

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PleD


Contents

Intro

Protomer

Diguanylate cyclase PleD (1w25)

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Substrate binding site

2v0n

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Allosteric product binding site

Allosteric product binding site

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C-di-GMP


Primary inhibition site (Ip)


Secondary inhibition site (Is)


Primary and secondary inhibition sites





Two conformations

non-activated (1w25)
non-activated (1w25)
activated (BeF3- modified; 2v0n)
activated (BeF3- modified; 2v0n)


non-activated (1w25)

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activated (BeF3- modified; 2v0n)

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Non-activated conformation

1w25

1w25

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: , ,



















Activated conformation

2v0n

2v0n

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Tilman Schirmer

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