1rw1

From Proteopedia

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Revision as of 21:15, 24 November 2007

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spinqualitylabelsall models 1rw1, resolution 1.02Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

YFFB (PA3664) PROTEIN

Overview

BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an, uncharacterized protein of 13 kDa molecular weight with a marginal, sequence similarity to arsenate reductase from Escherichia coli. The, crystal structure determination of YffB was undertaken as part of a, structural genomics effort in order to assist with the functional, assignment of the protein. RESULTS: The structure was determined at 1.0 A, resolution by single-wavelength anomalous diffraction. The fold is very, similar to that of arsenate reductase, which is an extension of the, thioredoxin fold. CONCLUSION: Given the conservation of the functionally, important residues and the ability to bind glutathione, YffB is likely to, function as a GSH-dependent thiol reductase.

About this Structure

1RW1 is a Single protein structure of sequence from Pseudomonas aeruginosa pao1 with IPA as ligand. Full crystallographic information is available from OCA.

Reference

Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:15102337

Page seeded by OCA on Sat Nov 24 23:23:13 2007