User:Tilman Schirmer/Sandbox 203
From Proteopedia
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==References== | ==References== | ||
PlzD structure [[1yln]]: | PlzD structure [[1yln]]: | ||
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Zhang R, Zhou M, Moy S, Collart FR, Joachimiak A. 2005. The crystal structure of | Zhang R, Zhou M, Moy S, Collart FR, Joachimiak A. 2005. The crystal structure of | ||
the hypothetical protein vca0042 from Vibrio cholerae O1. Joint Center of Structural Genomics (JCSG). | the hypothetical protein vca0042 from Vibrio cholerae O1. Joint Center of Structural Genomics (JCSG). | ||
Revision as of 09:33, 15 July 2009
C-di-GMP receptors with PilZ domain
PlzD
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from Vibrio cholerae is composed of a and a C-terminal domain (with very similar fold).
The c-di-GMP is formed by arginine residues of the inter-domain linker and the PlzD domain surface .
PlzD in complex with c-di-GMP
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Upon complex formation the relative domain arrangement is (compare with 1yln above), .
References
PlzD structure 1yln:
Zhang R, Zhou M, Moy S, Collart FR, Joachimiak A. 2005. The crystal structure of the hypothetical protein vca0042 from Vibrio cholerae O1. Joint Center of Structural Genomics (JCSG).
PlzD - c-di-GMP structure 2rde:
- Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF. The structural basis of cyclic diguanylate signal transduction by PilZ domains. EMBO J. 2007 Dec 12;26(24):5153-66. Epub 2007 Nov 22. PMID:18034161
