C-di-GMP
From Proteopedia
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| - | <applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP' /> | + | <applet load='2v0n' scene='C-di-GMP/C-di-gmp/1' size='400' frame='true' align='right' caption='cyclic di-GMP [[2v0n]]' /> |
C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria. | ||
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| + | ==References== | ||
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| + | <ref group="xtra">PMID:19287449</ref><ref group="xtra">PMID:16895465</ref> | ||
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Revision as of 10:08, 15 July 2009
Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)
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C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.
is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.
Several protein structures involved in c-di-GMP signaling have been determined (reviewed in User:Tilman_Schirmer/Sandbox_200).
References
Reviews:
- Hengge R. Principles of c-di-GMP signalling in bacteria. Nat Rev Microbiol. 2009 Apr;7(4):263-73. PMID:19287449 doi:10.1038/nrmicro2109
- Jenal U, Malone J. Mechanisms of cyclic-di-GMP signaling in bacteria. Annu Rev Genet. 2006;40:385-407. PMID:16895465 doi:10.1146/annurev.genet.40.110405.090423
