C-di-GMP

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 22: Line 22:
<ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref>
<ref group="xtra">PMID:2158107</ref><ref group="xtra">PMID: 8286055 </ref>
<references group="xtra"/>
<references group="xtra"/>
 +
 +
[[Category: C-di-GMP]]

Revision as of 11:31, 15 July 2009

cyclic di-GMP, as found in complex with the diguanylate cyclase PleD 2v0n

Drag the structure with the mouse to rotate

Cyclic di-GMP, (bis-(3'-5') cyclic diguanylic acid)


C-di-GMP is a second messenger that mediates the regulation of cell-surface associated traits in bacteria.

is a cyclic dinucleotide with a 12-membered macro-cycle composed of the the phosphate and ribose moieties. It tends to associate to form with intercalated, stacked bases.


Several protein structures involved in c-di-GMP signaling have been determined (see User:Tilman_Schirmer/Sandbox_200).



UNIPROT link









References

Reviews:

  • Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proc Natl Acad Sci U S A. 1990 Apr;87(8):3235-9. PMID:2158107
  • Guan Y, Gao YG, Liaw YC, Robinson H, Wang AH. Molecular structure of cyclic diguanylic acid at 1 A resolution of two crystal forms: self-association, interactions with metal ion/planar dyes and modeling studies. J Biomol Struct Dyn. 1993 Oct;11(2):253-76. PMID:8286055

Proteopedia Page Contributors and Editors (what is this?)

Tilman Schirmer

Retrieved from "http://52.214.119.220/wiki/index.php/C-di-GMP"
Personal tools