1fml

From Proteopedia

(Difference between revisions)
Jump to: navigation, search

OCA (Talk | contribs)
(New page: 200px<br /><applet load="1fml" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fml, resolution 2.75&Aring;" /> '''CRYSTAL STRUCTURE OF...)
Next diff →

Revision as of 21:55, 24 November 2007

Image:1fml.gif

1fml, resolution 2.75Å

Drag the structure with the mouse to rotate

CRYSTAL STRUCTURE OF RETINOL DEHYDRATASE IN A COMPLEX WITH RETINOL AND PAP

Overview

We report here the crystal structure of retinol dehydratase, an enzyme, that catalyzes the synthesis of anhydroretinol. The enzyme is a member of, the sulfotransferase superfamily and its crystal structure reveals the, insertion of a helical lid into a canonical sulfotransferase fold., Site-directed mutations demonstrate that this inserted lid is necessary, for anhydroretinol production but not for sulfonation; thus, insertion of, a helical lid can convert a sulfotransferase into a dehydratase.

About this Structure

1FML is a Single protein structure of sequence from Spodoptera frugiperda with CA, A3P and RTL as ligands. Full crystallographic information is available from OCA.

Reference

A helical lid converts a sulfotransferase to a dehydratase., Pakhomova S, Kobayashi M, Buck J, Newcomer ME, Nat Struct Biol. 2001 May;8(5):447-51. PMID:11323722

Page seeded by OCA on Sun Nov 25 00:03:28 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1fml"
Personal tools