3ggc

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3ggc.jpg|left|200px]]
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The entry 3ggc is ON HOLD until Paper Publication
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{{STRUCTURE_3ggc| PDB=3ggc | SCENE= }}
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Authors: Keough, D.T., Hockov, D., Hol, A., Naesens, L., Skinner-Adams, T., De Jersey, J., Guddat, L.W.
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===Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)hypoxanthine===
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Description: Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)hypoxanthine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 15 09:53:28 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19527031 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19527031}}
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==About this Structure==
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3GGC is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GGC OCA].
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==Reference==
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<ref group="xtra">PMID:19527031</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Guddat, L W.]]
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[[Category: Jersey, J.]]
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[[Category: Keough, D T.]]
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[[Category: Acetylation]]
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[[Category: Acyclic nucleoside phosphonate]]
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[[Category: Cytoplasm]]
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[[Category: Disease mutation]]
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[[Category: Glycosyltransferase]]
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[[Category: Gout]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Phosphoribosyltransferase]]
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[[Category: Purine salvage]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 12:52:16 2009''

Revision as of 09:52, 19 August 2009

Image:3ggc.jpg

Template:STRUCTURE 3ggc

Human hypoxanthine-guanine phosphoribosyltransferase in complex with 9-(2-phosphonoethoxyethyl)hypoxanthine

Template:ABSTRACT PUBMED 19527031

About this Structure

3GGC is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Keough DT, Hockova D, Holy A, Naesens LM, Skinner-Adams TS, Jersey J, Guddat LW. Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J Med Chem. 2009 Jul 23;52(14):4391-9. PMID:19527031 doi:10.1021/jm900267n

Page seeded by OCA on Wed Aug 19 12:52:16 2009

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