3e51

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3e51.jpg|left|200px]]
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The entry 3e51 is ON HOLD until Aug 12 2010
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{{STRUCTURE_3e51| PDB=3e51 | SCENE= }}
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Authors: Han, Q., Showalter, R.E., Zhao, Q., Kissinger, C.R.
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===Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor===
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Description: Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 10 12:34:06 2008''
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{{ABSTRACT_PUBMED_18796353}}
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==About this Structure==
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3E51 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E51 OCA].
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==Reference==
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<ref group="xtra">PMID:18796353</ref><references group="xtra"/>
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Viruses]]
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[[Category: Han, Q.]]
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[[Category: Kissinger, C R.]]
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[[Category: Showalter, R E.]]
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[[Category: Zhao, Q.]]
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[[Category: Nucleotide-binding]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Protein-ligand complex]]
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[[Category: Rna-directed rna polymerase]]
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[[Category: Transcription]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:06:17 2009''

Revision as of 10:06, 19 August 2009

Image:3e51.jpg

Template:STRUCTURE 3e51

Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor

Template:ABSTRACT PUBMED 18796353

About this Structure

3E51 is a 2 chains structure of sequences from Viruses. Full crystallographic information is available from OCA.

Reference

  • Dragovich PS, Blazel JK, Ellis DA, Han Q, Kamran R, Kissinger CR, LeBrun LA, Li LS, Murphy DE, Noble M, Patel RA, Ruebsam F, Sergeeva MV, Shah AM, Showalter RE, Tran CV, Tsan M, Webber SE, Kirkovsky L, Zhou Y. Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)- 5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5635-9. Epub 2008 Aug 29. PMID:18796353 doi:10.1016/j.bmcl.2008.08.094

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