3gep

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3gep.jpg|left|200px]]
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The entry 3gep is ON HOLD until Paper Publication
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{{STRUCTURE_3gep| PDB=3gep | SCENE= }}
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Authors: Guddat, L.W., Keough, D.T., de Jersey, J.
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===Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine===
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Description: Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 4 07:17:38 2009''
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{{ABSTRACT_PUBMED_19527031}}
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==About this Structure==
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3GEP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEP OCA].
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==Reference==
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<ref group="xtra">PMID:19527031</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Guddat, L W.]]
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[[Category: Jersey, J.]]
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[[Category: Keough, D T.]]
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[[Category: Acetylation]]
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[[Category: Acyclic nucleoside phosphonate]]
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[[Category: Cytoplasm]]
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[[Category: Disease mutation]]
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[[Category: Glycosyltransferase]]
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[[Category: Gout]]
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[[Category: Magnesium]]
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[[Category: Malarial chemotherapeutic]]
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[[Category: Metal-binding]]
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[[Category: Phosphoribosyltransferase]]
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[[Category: Purine salvage]]
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[[Category: Purine salvage pathway]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 19 13:07:14 2009''

Revision as of 10:07, 19 August 2009

Template:STRUCTURE 3gep

Human hypoxanthine guanine phosphoribosyltranserfase in complex with (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)guanine

Template:ABSTRACT PUBMED 19527031

About this Structure

3GEP is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Keough DT, Hockova D, Holy A, Naesens LM, Skinner-Adams TS, Jersey J, Guddat LW. Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. J Med Chem. 2009 Jul 23;52(14):4391-9. PMID:19527031 doi:10.1021/jm900267n

Page seeded by OCA on Wed Aug 19 13:07:14 2009

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