3h6t
From Proteopedia
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+ | [[Image:3h6t.png|left|200px]] | ||
- | The | + | <!-- |
+ | The line below this paragraph, containing "STRUCTURE_3h6t", creates the "Structure Box" on the page. | ||
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+ | {{STRUCTURE_3h6t| PDB=3h6t | SCENE= }} | ||
- | + | ===Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and cyclothiazide at 2.25 A resolution=== | |
- | Description: Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and cyclothiazide at 2.25 A resolution | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
+ | The line below this paragraph, {{ABSTRACT_PUBMED_19591837}}, adds the Publication Abstract to the page | ||
+ | (as it appears on PubMed at http://www.pubmed.gov), where 19591837 is the PubMed ID number. | ||
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+ | {{ABSTRACT_PUBMED_19591837}} | ||
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+ | ==About this Structure== | ||
+ | 3H6T is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6T OCA]. | ||
+ | |||
+ | ==Reference== | ||
+ | <ref group="xtra">PMID:19591837</ref><ref group="xtra">PMID:11086992</ref><ref group="xtra">PMID:12015593</ref><references group="xtra"/> | ||
+ | [[Category: Rattus norvegicus]] | ||
+ | [[Category: Gajhede, M.]] | ||
+ | [[Category: Hald, H.]] | ||
+ | [[Category: Kastrup, J S.]] | ||
+ | [[Category: Allosteric modulation]] | ||
+ | [[Category: Ampa receptor ligand-binding core]] | ||
+ | [[Category: Cyclothiazide]] | ||
+ | [[Category: Iglur2 s1s2j-n754]] | ||
+ | [[Category: Membrane protein]] | ||
+ | |||
+ | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 9 08:32:29 2009'' |
Revision as of 05:32, 9 September 2009
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and cyclothiazide at 2.25 A resolution
Template:ABSTRACT PUBMED 19591837
About this Structure
3H6T is a 3 chains structure of sequences from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Hald H, Ahring PK, Timmermann DB, Liljefors T, Gajhede M, Kastrup JS. Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2. J Mol Biol. 2009 Sep 4;391(5):906-17. Epub 2009 Jul 8. PMID:19591837 doi:10.1016/j.jmb.2009.07.002
- Armstrong N, Gouaux E. Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron. 2000 Oct;28(1):165-81. PMID:11086992
- Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E. Mechanism of glutamate receptor desensitization. Nature. 2002 May 16;417(6886):245-53. PMID:12015593 doi:10.1038/417245a
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