1dys

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(New page: 200px<br /> <applet load="1dys" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dys, resolution 1.6&Aring;" /> '''ENDOGLUCANASE CEL6B ...)
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==About this Structure==
==About this Structure==
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1DYS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DYS OCA]].
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1DYS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Humicola_insolens Humicola insolens]]. Active as [[http://en.wikipedia.org/wiki/Hydrolase Hydrolase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.4 3.2.1.4]]. Structure known Active Sites: CIA and CIB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DYS OCA]].
==Reference==
==Reference==
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[[Category: hydrolase]]
[[Category: hydrolase]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 16:20:31 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:34:39 2007''

Revision as of 06:29, 30 October 2007


1dys, resolution 1.6Å

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ENDOGLUCANASE CEL6B FROM HUMICOLA INSOLENS

Overview

Cellulases are traditionally classified as either endoglucanases or, cellobiohydrolases on the basis of their respective catalytic activities, on crystalline cellulose, which is generally hydrolysed more efficiently, only by the cellobiohydrolases. On the basis of the Trichoderma reesei, cellobiohydrolase II structure, it was proposed that the active-site, tunnel of cellobiohydrolases permitted the processive hydrolysis of, cellulose, whereas the corresponding endoglucanases would display open, active-site clefts [Rouvinen, Bergfors, Teeri, Knowles and Jones (1990), Science 249, 380-386]. Glycoside hydrolase family 6 contains both, cellobiohydrolases and endoglucanases. The structure of the catalytic core, of the family 6 endoglucanase Cel6B from Humicola insolens has been solved, by ... [(full description)]

About this Structure

1DYS is a [Single protein] structure of sequence from [Humicola insolens]. Active as [Hydrolase], with EC number [3.2.1.4]. Structure known Active Sites: CIA and CIB. Full crystallographic information is available from [OCA].

Reference

Structure and function of Humicola insolens family 6 cellulases: structure of the endoglucanase, Cel6B, at 1.6 A resolution., Davies GJ, Brzozowski AM, Dauter M, Varrot A, Schulein M, Biochem J. 2000 May 15;348 Pt 1:201-7. PMID:10794732

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