3e8n
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
{{Seed}} | {{Seed}} | ||
| - | [[Image:3e8n. | + | [[Image:3e8n.png|left|200px]] |
<!-- | <!-- | ||
| Line 12: | Line 12: | ||
===X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP=== | ===X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP=== | ||
| + | |||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19706763}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19706763 is the PubMed ID number. | ||
| + | --> | ||
| + | {{ABSTRACT_PUBMED_19706763}} | ||
==About this Structure== | ==About this Structure== | ||
3E8N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8N OCA]. | 3E8N is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8N OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19706763</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mitogen-activated protein kinase kinase]] | [[Category: Mitogen-activated protein kinase kinase]] | ||
| Line 34: | Line 43: | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:26:28 2009'' |
Revision as of 05:26, 16 September 2009
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP
Template:ABSTRACT PUBMED 19706763
About this Structure
3E8N is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Iverson C, Larson G, Lai C, Yeh LT, Dadson C, Weingarten P, Appleby T, Vo T, Maderna A, Vernier JM, Hamatake R, Miner JN, Quart B. RDEA119/BAY 869766: a potent, selective, allosteric inhibitor of MEK1/2 for the treatment of cancer. Cancer Res. 2009 Sep 1;69(17):6839-47. Epub 2009 Aug 25. PMID:19706763 doi:10.1158/0008-5472.CAN-09-0679
Page seeded by OCA on Wed Sep 16 08:26:28 2009
Categories: Homo sapiens | Mitogen-activated protein kinase kinase | Wang, Z M. | Yan, S. | Acetylation | Atp-binding | Disease mutation | Kinase | Mek1 | Mek1-rdea119 complex | Nucleotide-binding | Phosphoprotein | Protein kinase-ligand-mgatp complex | Rdea-119 | Rdea119 | Serine/threonine-protein kinase | Transferase | Tyrosine-protein kinase
