3hrf

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3hrf.jpg|left|200px]]
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The entry 3hrf is ON HOLD until Paper Publication
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{{STRUCTURE_3hrf| PDB=3hrf | SCENE= }}
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Authors: Hindie, V., Alzari, P.M., Biondi, R.M.
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===Crystal structure of Human PDK1 kinase domain in complex with an allosteric activator bound to the PIF-pocket===
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Description: Crystal structure of Human PDK1 kinase domain in complex with an allosteric activator bound to the PIF-pocket
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 22 20:33:11 2009''
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(as it appears on PubMed at http://www.pubmed.gov), where 19718043 is the PubMed ID number.
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{{ABSTRACT_PUBMED_19718043}}
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==About this Structure==
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3HRF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HRF OCA].
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==Reference==
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<ref group="xtra">PMID:19718043</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Alzari, P M.]]
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[[Category: Biondi, R M.]]
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[[Category: Hindie, V.]]
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[[Category: Activation loop]]
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[[Category: Agc kinase]]
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[[Category: Allostery]]
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[[Category: Alpha-c helix]]
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[[Category: Alternative splicing]]
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[[Category: Atp binding]]
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[[Category: Atp-binding]]
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[[Category: Cytoplasm]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Pdk1]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Pif-pocket]]
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[[Category: Serine/threonine-protein kinase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 16 08:56:49 2009''

Revision as of 05:56, 16 September 2009

Image:3hrf.jpg

Template:STRUCTURE 3hrf

Crystal structure of Human PDK1 kinase domain in complex with an allosteric activator bound to the PIF-pocket

Template:ABSTRACT PUBMED 19718043

About this Structure

3HRF is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hindie V, Stroba A, Zhang H, Lopez-Garcia LA, Idrissova L, Zeuzem S, Hirschberg D, Schaeffer F, Jorgensen TJ, Engel M, Alzari PM, Biondi RM. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64. Epub 2009 Aug 30. PMID:19718043 doi:10.1038/nchembio.208

Page seeded by OCA on Wed Sep 16 08:56:49 2009

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