2puq
From Proteopedia
(Difference between revisions)
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==Disease== | ==Disease== | ||
| - | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Angiotensin I-converting enzyme, benign serum increase OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Alzheimer disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], | + | Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Renal tubular dysgenesis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Angiotensin I-converting enzyme, benign serum increase OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Alzheimer disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Microvascular complications of diabetes 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], Myocardial infarction, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]], SARS, progression of OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=106180 106180]] |
==About this Structure== | ==About this Structure== | ||
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[[Category: Rasmussen, H B.]] | [[Category: Rasmussen, H B.]] | ||
[[Category: Active site inhibitor]] | [[Category: Active site inhibitor]] | ||
| + | [[Category: Blood clotting]] | ||
[[Category: Substrate profile]] | [[Category: Substrate profile]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Sep 21 19:56:17 2009'' |
Revision as of 16:56, 21 September 2009
Contents |
Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Template:ABSTRACT PUBMED 17456045
Disease
Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500], Renal tubular dysgenesis OMIM:[106180], Angiotensin I-converting enzyme, benign serum increase OMIM:[106180], Alzheimer disease, susceptibility to OMIM:[106180], Microvascular complications of diabetes 3 OMIM:[106180], Myocardial infarction, susceptibility to OMIM:[106180], SARS, progression of OMIM:[106180]
About this Structure
2PUQ is a 4 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 2pmm. Full crystallographic information is available from OCA.
Reference
- Larsen KS, Ostergaard H, Bjelke JR, Olsen OH, Rasmussen HB, Christensen L, Kragelund BB, Stennicke HR. Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa. Biochem J. 2007 Aug 1;405(3):429-38. PMID:17456045 doi:http://dx.doi.org/10.1042/BJ20061901
Page seeded by OCA on Mon Sep 21 19:56:17 2009
