2aw1
From Proteopedia
(Difference between revisions)
| Line 33: | Line 33: | ||
[[Category: Supuran, C T.]] | [[Category: Supuran, C T.]] | ||
[[Category: Carbonic anhydrase]] | [[Category: Carbonic anhydrase]] | ||
| + | [[Category: Lyase]] | ||
[[Category: Protein-inhibitor complex]] | [[Category: Protein-inhibitor complex]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:12:18 2009'' |
Revision as of 05:12, 23 September 2009
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib
Template:ABSTRACT PUBMED 16290146
About this Structure
2AW1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. Bioorg Med Chem Lett. 2006 Jan 15;16(2):437-42. Epub 2005 Nov 14. PMID:16290146 doi:10.1016/j.bmcl.2005.09.040
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