2w7x
From Proteopedia
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| + | {{STRUCTURE_2w7x| PDB=2w7x | SCENE= }} | ||
| - | + | ===CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019=== | |
| - | Description: Cellular inhibition of checkpoint kinase 2 and potentiation of cytotoxic drugs by novel Chk2 inhibitor PV1019 | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19741151}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19741151 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19741151}} | ||
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| + | ==About this Structure== | ||
| + | 2W7X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7X OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19741151</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Non-specific serine/threonine protein kinase]] | ||
| + | [[Category: Caplen, N J.]] | ||
| + | [[Category: Caredellina, J H.]] | ||
| + | [[Category: Connelly, J.]] | ||
| + | [[Category: Jobson, A G.]] | ||
| + | [[Category: Kondapaka, S.]] | ||
| + | [[Category: Llamas, J.]] | ||
| + | [[Category: Lorenzi, P L.]] | ||
| + | [[Category: Lountos, G T.]] | ||
| + | [[Category: Monks, A.]] | ||
| + | [[Category: Onda, A.]] | ||
| + | [[Category: Pommier, Y.]] | ||
| + | [[Category: Self, C.]] | ||
| + | [[Category: Shoemaker, R H.]] | ||
| + | [[Category: Tropea, J E.]] | ||
| + | [[Category: Waugh, D S.]] | ||
| + | [[Category: Zhang, G.]] | ||
| + | [[Category: Alternative splicing]] | ||
| + | [[Category: Atp-binding]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Chk2 inhibitor]] | ||
| + | [[Category: Co-crystal structure]] | ||
| + | [[Category: Disease mutation]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Li-fraumeni syndrome]] | ||
| + | [[Category: Magnesium]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Nucleotide-binding]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Polymorphism]] | ||
| + | [[Category: Potentiation]] | ||
| + | [[Category: Proto-oncogene]] | ||
| + | [[Category: Serine/threonine-protein kinase]] | ||
| + | [[Category: Transferase]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 23 08:39:34 2009'' | ||
Revision as of 05:39, 23 September 2009
CELLULAR INHIBITION OF CHECKPOINT KINASE 2 AND POTENTIATION OF CYTOTOXIC DRUGS BY NOVEL CHK2 INHIBITOR PV1019
Template:ABSTRACT PUBMED 19741151
About this Structure
2W7X is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y. Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide]. J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. Epub 2009 Sep 9. PMID:19741151 doi:10.1124/jpet.109.154997
Page seeded by OCA on Wed Sep 23 08:39:34 2009
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Caplen, N J. | Caredellina, J H. | Connelly, J. | Jobson, A G. | Kondapaka, S. | Llamas, J. | Lorenzi, P L. | Lountos, G T. | Monks, A. | Onda, A. | Pommier, Y. | Self, C. | Shoemaker, R H. | Tropea, J E. | Waugh, D S. | Zhang, G. | Alternative splicing | Atp-binding | Cell cycle | Chk2 inhibitor | Co-crystal structure | Disease mutation | Kinase | Li-fraumeni syndrome | Magnesium | Metal-binding | Nucleotide-binding | Nucleus | Phosphoprotein | Polymorphism | Potentiation | Proto-oncogene | Serine/threonine-protein kinase | Transferase
