3jwt

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Image:3jwt.jpg

Template:STRUCTURE 3jwt

Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with N1-{(3'R,4'R)-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine

Template:ABSTRACT PUBMED 20337441

About this Structure

3JWT is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Delker SL, Ji H, Li H, Jamal J, Fang J, Xue F, Silverman RB, Poulos TL. Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J Am Chem Soc. 2010 Apr 21;132(15):5437-42. PMID:20337441 doi:10.1021/ja910228a

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