This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1aw6
From Proteopedia
|
GAL4 (CD), NMR, 24 STRUCTURES
Overview
We have refined the solution structure of cadmium-bound GAL4 and present, its 15N and 1H NMR assignments. The root-mean-square (rms) deviation to, the average structure was 0.4 +/- 0.05 A for backbone atoms, and 0.9 +/-, 0.1 A for all heavy atoms. The three-bond heteronuclear 3J(113Cd,1H), coupling constants were found to disobey a Karplus-type relationship, which was attributable to the unusual constraints imposed by the, bimetal-thiolate cluster in GAL4. We conclude that the structural, parameters that correlate to 3J(113Cd,1H) are complex.
About this Structure
1AW6 is a [Single protein] structure of sequence from [Saccharomyces cerevisiae] with CD as [ligand]. This structure superseeds the now removed PDB entry 125D. Structure known Active Sites: CD4 and CD5. Full crystallographic information is available from [OCA].
Reference
Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination., Baleja JD, Thanabal V, Wagner G, J Biomol NMR. 1997 Dec;10(4):397-401. PMID:9460244
Page seeded by OCA on Tue Oct 30 10:42:05 2007
